-The Bartelle lab develops probes, reporters, and sensors to assay the diverse molecular signaling of whole living animals, from model systems to humans.
-We prioritize maximizing the scale of data collection while minimizing invasiveness to resolve organismal biology without disrupting it, and to apply our technologies clinically, if needed.
-Our platform technology is magnetic resonance imaging, the only modality with adequate scale and resolution to cover whole organs and organisms.
-Our primary application is the development and degeneration of the mammalian brain. The interplay of diverse cell types influenced by metabolism and inflammatory states makes the brain the most complex and least understood system in biology.