Curriculum Vitae

 

Ben BartelleCV2018_MIT

Benjamin B Bartelle PhD

bartelle “at” MIT “point” edu

____________________________________________________________________

ORCID ID: orcid.org/0000-0002-5044-369X

PEER REVIEWED PUBLICATIONS:

(*equal authorship, 7 first author research, 1 review)

Barandov A*, Bartelle BB*, Williamson CG, Loucks E, Jasanoff AP. Sensing intracellular calcium ions using a manganese-based MRI contrast agent. Nat Commun. 2019 Feb 22;10(1):897

Okada S*, Bartelle BB*, Li N, Breton-Provencher V, Lee J, Rodriguez E, Melican J, Bricault S, Sur M, Jasanoff AP. Calcium-dependent molecular fMRI using a magnetic nanosensor. Nature Nanotechnology 2018 Jun;13(6):473-477

Bartelle BB, Barandov A, Jasanoff A.Molecular fMRI. J Neurosci. 2016 Apr 13;36(15):4139-48. Review. PubMed PMID: 27076413; PubMed Central PMCID: PMC4829642.

Barandov A*, Bartelle BB*, Gonzalez BA, White WL, Lippard SJ, Jasanoff A. Membrane-Permeable Mn(III) Complexes for Molecular Magnetic Resonance Imaging of Intracellular Targets. Journal of the American Chemical Society. 2016 May 4;138(17):5483-6. Epub 2016 Apr 22. PubMed PMID: 27088782.

Bartelle BB, Mana MD, Suero-Abreu GA, Rodriguez JJ, Turnbull DH. Engineering an effective Mn-binding MRI reporter protein by subcellular targeting. Magnetic Resonance in Medicine. 2015 Dec;74(6):1750-7. Epub 2014 Dec 17. PubMed PMID: 25522343; PubMed Central PMCID: PMC4470876.

Bartelle BB, Szulc KU, Suero-Abreu GA, Rodriguez JJ, Turnbull DH. Divalent metal transporter, DMT1: a novel MRI reporter protein. Magnetic Resonance in Medicine. 2013 Sep;70(3):842-50 Epub 2012 Oct 12. PubMed PMID: 23065715; PubMed Central PMCID: PMC3587026.

Gruppi F*, Liang J*, Bartelle BB*, Royzen M, Turnbull DH, Canary JW. Supramolecular metal displacement allows on-fluorescence analysis of manganese(II) in living cells. Chemical Communications (Camb). 2012 Nov 11;48(87):10778-80. PubMed PMID: 23023093; PubMed Central PMCID: PMC3722360.

Bartelle BB, Berríos-Otero CA, Rodriguez JJ, Friedland AE, Aristizábal O, Turnbull DH. Novel genetic approach for in vivo vascular imaging in mice. Circulation Research. 2012 Mar 30;110(7):938-47. PubMed PMID: 22374133; PubMed Central PMCID: PMC3319022.

Bartelle BB*, Schwalm ME*, Li N, Barandov A, Williamson CG, Jasanoff AP. Calcium fMRI of sensory activation at high spatiotemporal resolution. (in preparation)

 

Contributing authorship:

Hai A, Spanoudaki SC, Bartelle BB, Jasanoff AP Wireless resonant circuits for the minimally invasive sensing of biophysical processes in magnetic resonance imaging. Nat Biomed Eng. 2019 Jan;3(1):69-78.

 Suero-Abreu GA, Aristizábal O, Bartelle BB, Volkova E, Rodríguez JJ, Turnbull DH. Multimodal Genetic Approach for Molecular Imaging of Vasculature in a Mouse Model of Melanoma. Mol Imaging Biol. 2017 Apr;19(2):203-214. PubMed PMID: 27677887; PubMed Central PMCID: PMC5400104.

Szulc KU, Lerch JP, Nieman BJ, Bartelle BB, Friedel M, Suero-Abreu GA, Watson C, Joyner AL, Turnbull DH. 4D MEMRI atlas of neonatal FVB/N mouse brain development. Neuroimage. 2015 Sep;118:49-62. PubMed PMID: 26037053; PubMed Central PMCID: PMC4554969.

Barch M, Okada S, Bartelle BB, Jasanoff A. Screen-based analysis of magnetic nanoparticle libraries formed using peptidic iron oxide ligands. Journal of the American Chemical Society. 2014 Sep 10;136(36):12516-9. PubMed PMID: 25158100; PubMed Central PMCID: PMC4160280.

Szulc KU, Nieman BJ, Houston EJ, Bartelle BB, Lerch JP, Joyner AL, Turnbull DH. MRI analysis of cerebellar and vestibular developmental phenotypes in Gbx2 conditional knockout mice. Magnetic Resonance in Medicine. 2013 Dec;70(6):1707-17. 2013 Feb 7. PubMed PMID: 23400959; PubMed Central PMCID: PMC3657598.

NCBI:

https://www.ncbi.nlm.nih.gov/sites/myncbi/benjamin.bartelle.1/bibliography/50378759/public/?sort=date&direction=ascending

INVITED TALKS:

Mount Sinai Medical Center

3/2018

Proceedings of the International Society of Magnetic Resonance in Medicine

“Molecular Imaging for Beginners: Introduction to ‘Cellular’ Imaging                         

5/2018

 

ABSTRACTS SELECTED FOR PRESENTATION:

Society for Neuroscience

Genetically targeted fMRI 

11/2019

Proceedings of the World Molecular Imaging Congress

“Sensing intracellular calcium ions using a manganese-based MRI contrast agent.”       

09/2018

Boston Symposium on Careers and Collaboration in Science

“Calcium Dependent Molecular fMRI” 

6/2017

Biomedical Engineering Society Annual Meeting

“Protein Engineering for Molecular Imaging Applications” 

10/2012

Proceedings of the International Society of Magnetic Resonance in Medicine

“Divalent Metal Transport Protein DMT1: A Novel MRI Reporter.” 

5/2011

Proceedings of the World Molecular Imaging Congress

“Divalent Metal Transport Protein DMT1: A Novel MRI Reporter.”

9/2010

Proceedings of the World Molecular Imaging Congress

“Transgenic Mice for Multimodal Imaging of Angiogenesis.”

9/2009

Proceedings of the International Society of Magnetic Resonance in Medicine

“MntR, an MRI reporter provides cellular T1 contrast”

4/2008

Proceedings of the International Society of Magnetic Resonance in Medicine

A New MRI Reporter Gene: Mn Binding Protein Produces T1 Cellular Contrast.”

5/2007

 

AWARDS:

Boston Symposium on Careers and Collaboration in Science Outstanding Presentation:   

2017

MIT School of Science SPOT award:

2016

World Molecular Imaging Congress Travel Award: 

2010

NYU GSAS Dean’s Travel Award:

2010

Gordon Conference Travel Award:

2010

World Molecular Imaging Congress Travel Award:

2009

International Society of Magnetic Resonance in Medicine Travel Award:

2008

International Society of Magnetic Resonance in Medicine Travel Award:

2007

NYU GSAS Dean’s Travel Award:

2007

NIH Graduate Partnerships Program Fellowship: 

2004-2005

RECENT RESEARCH SUPPORT:

MGH-MIT Grand Challenge Seed Grant (Jasanoff, PI cowritten)

7/15-8/18

Title: Bioconjugate neurotransmitter sensors for molecular MRI

Project goals: Develop innovative bioconjugate molecular neuroimaging probes

NIH U01-NS090451 (BRAIN Initiative; Jasanoff, PI cowritten)

Title: Calcium sensors for molecular fMRI

Project Goals: Synthesize and apply intracellular calcium sensors for molecular-level functional neuroimaging

10/14-9/17

NIH R21-MH102470 (Jasanoff, PI cowritten)

Title: Amino acid neurotransmitter sensors for MRI

Project Goals: Develop and apply amino acid neurotransmitter sensors for functional neuroimaging

9/13-8/15

RESEARCH EXPERIENCE:

MIT                                       Post Doctoral Associate        Alan P Jasanoff

Multidisciplinary technology development for molecular fMRI of the mammalian brain.

6/12 –

New York University           PhD Candidate                     Daniel H Turnbull          

Engineering of novel reporter proteins and neonatal imaging methods for MRI and ultrasound.

9/04 – 5/12

Sentigen Biosciences         Research Associate             Kevin J Lee                  

Molecular tool development for receptor neurobiology, inventors of the “Tango” GPCR assay.

6/01 – 8/04

Cold Spring Harbor Labs   Molecular Biologist                Robert A Martienssen  

High throughput transgenic library construction for the Arabidopsis Sequencing Consortium.

2/00 – 6/01

Advanced Medicine Inc.     Chemist                                 David Oare   

Combinatorial chemistry for psychiatric pharmacology.

12/98 – 8/99

TEACHING EXPERIENCE:

MIT Biomaker Space                                                Maxine Jonas  

Lab manager and mentor for biotechnology outreach and education.

2/17 –5/19

MIT                               Neurotechnology in Action    Alan Jasanoff / Ed Boyden

Teaching assistant: MRI lab section

6/15 –

NYU Med                     Physics for MCAT                 Mekbib Gameda          

Course planning and instructor for program assisting underrepresented minorities in medicine.

3/09 – 6/11

UCSC Chemistry       Organic/Biochemistry                   Joseph Konopelski  

Lab Teaching Assistant.

9/97 – 12/98

UNDERGRADUATE MENTORSHIP:

Jade Daher                                                    MIT 2022

2017-

Catherine Williamson                                   MIT 2019

2015-

Accepted UCLA Medical School

Melat Anteneh                                               MIT 2020

2017

Andrew Tang                                                MIT 2017

2014-2015

Instructor, MIT Emergency Medical Services

Emily Loucks                                                Wellesly 2016

2014-2016

Research Associate Gensun Biopharma Inc.

Justin L Reid                                                 MIT 2018

2014

Emily J Young                                               MIT 2018 

2014

Cofounder Okoa Ambulance

William L White                                             MIT 2017

2014-2015

University of Washington Department of Bioengineering fall 2018

Stephanie Ihezie                                                 MIT 2015

2012-2014

University of Texas Southwestern

Anne Friedland MD              Tufts School of Medicine 2014 

2008 -2010

Resident University of Maryland Medical center

Joe J Rodriguez                   Ponce School of Medicine 2015

2008-2012  

Resident University of Texas Health